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Affymetrix GeneChip® miRNA Array
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The GeneChip® miRNA Array is a powerful tool for studying the role of microRNAs (miRNAs) and their importance in cancer and other diseases. In addition, miRNA studies facilitate the discovery of biomarkers and disease signatures.
Non-coding RNAs are emerging as a major component of the regulatory circuitry that underlies the development and physiology of complex organisms. miRNAs are small, single-stranded RNAs that regulate gene expression by partial complementary base pairing to specific mRNAs. This annealing inhibits protein translation and in some cases facilitates the degradation of mRNA.
The GeneChip miRNA Array also includes human small nucleolar RNAs (snoRNAs and scaRNAs), which are short, non-translated RNAs that play a role in processing of ribosomal RNAs following transcription. snoRNAs have also been implicated in the regulation of alternative splicing.
The GeneChip miRNA Array solution offers the following:
Unmatched Coverage – Content from 71 species including human, mouse, rat, canine and monkey featured on one array make this the most powerful miRNA analysis platform for both research and pharmaceutical drug development.
Specialized miRNA Labeling Assay – Enhanced labeling chemistry yields sensitivity less than 10 attomole with industry-leading low noise to signal ratios (CV <10%), maximizing your data output. Total assay time is less than 45 minutes and this is the only miRNA assay with in-process quality control.
Low Cost miRNA Screening – The lowest price per sample microarray-based miRNA screening platform available on the market today.
Complete Analysis Solution from Millennium Science – From data QC using the free QCToolBox from Affymetrix to high-powered statistical analysis using the dedicated miRNA analysis module from Partek Genomics Suite, Millennium Science has all of your downstream analysis needs covered in the one spot.
The miRNA array assay consists of the following components from Affymetrix and Genisphere:
Affymetrix GeneChip® miRNA Array
- The most comprehensive miRNA coverage with multiple organisms on a single array
- Human, mouse, rat, canine, and monkey - all important species for research and pharmaceutical drug development
- Sanger miRNA database V11 content and additional human small nuclear RNAs (snoRNAs and scaRNAs)
- miRNA profiling on the industry's most reliable microarray platform
- Arrays are synthesized using Affymetrix' high-quality photolithography process to ensure optimal performance
- Contains controls to ensure success of your experiment
- Investment leverage
- Leverage your existing Affymetrix instrument - cost savings and convenience
Affymetrix miRNA QC Tool
Free miRNA QC Tool for data summarization, normalization and quality control.
Genisphere FlashTag™ Biotin RNA Labeling Kits for use with Affymetrix® miRNA Arrays:
- Reproducibility: CVs = 10%
- Sensitivity: = 10 attomoles
- Dynamic Range: 4 log10
- Specificity: 1 nucleotide discrimination
- Rapid, 45 minute Labeling of Total RNA
- In-Process Labeling QC Assay
- Low input amounts: 0.1 - 3µg total RNA
PART NUMBERS
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Affymetrix |
901324 |
GeneChip miRNA Array - 2 pack |
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Affymetrix |
901325 |
GeneChip miRNA Array - 6 pack |
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Affymetrix |
901326 |
GeneChip miRNA Array - 30 pack |
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Affymetrix |
900454 |
GeneChip Hyb Control kit - 30 reaction |
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Affymetrix |
900720 |
GeneChip Hyb/Wash/Stain kit - 30 reaction |
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Genisphere |
FT10AFYB |
FlashTag Biotin RNA Labeling Kit - 10 reaction |
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Genisphere |
FT30AFYB |
FlashTag Biotin RNA Labeling Kit - 30 reaction |
MORE INFORMATION
Affymetrix miRNA Array website
Genisphere FlashTag website
Email us or call us on 1800 678 242 (Australia) or 0800 507 896 (New Zealand)
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