Caliper
Microfluidics, Lab Automation & Liquid Handling
LabChip Systems
With nearly 20 years of microfluidics experience, Caliper Life Sciences continues to lead the industry in microfluidics technologies and innovations. Whether your research is focused on protein structure, genomic analysis, or compound screening, Caliper has developed transforming instrumentation that leverage the benefits of microfluidics technology, improving data quality and accelerating your research.
LABCHIP GX/ GXII
Complete solution for protein analysis and quantitation
- Accurate analysis of protein samples to accelerate optimization
- Quantitate molecular weight, concentration and purity in seconds
- Compatible with LabChip DNA and RNA assays
- Flexible with 96 and 384 well compatibility
- Comprehensive and quantitative analysis with LabChip GX software
The LabChip GXII is a complete solution for consistent and precise analysis of protein samples, and is an ideal instrument for protein research users. Whether it is quantitating monoclonal antibody titers, optimizing protein expression conditions, or rapidly screening IgG N-glycan profiles, the LabChip GXII is the perfect benchtop tool to accelerate your research and meet your goals. Leveraging microfluidics technology the LabChip GXII eliminates the need to handle time consuming SDS page gels, and provides superior results for less time and money.
When speed, accuracy and ease-of-use are paramount, the LabChip GXII is the perfect solution. With sample acquisition time under 40 seconds the instrument can thoroughly analyze 96 protein samples in less than an hour, virtually eliminating throughput bottlenecks and improving efficiency. In addition to the instrument, the complete system also includes the LabChip GX software for data analysis. This advanced data management suite allows users to visualize results via an electropherogram or virtual gel view. Additionally it provides data in tabular form, which can then be analyzed or easily exported into a spreadsheet format.
LABCHIP XT
Advanced Nucleic Acid Size Selection and Collection
- Reduce wasted "non-align" reads with tight size selection
- Increase average read length by excluding shorter fragments
- Faster sample processing maximizes use of sequencer
- Reduce waste and exposure to harmful reagents
Nucleic Acid Fractionation
The LabChip XT fractionation system performs fast, automated nucleic acid fractionation accurately and reproducibly. The resulting sample is tightly sized and is delivered in a sequencing compatible buffer. The XT improves laboratory efficiency and provides sizing that is difficult to obtain using manual methods. Data is displayed digitally and non-fractionated sample can be recollected and used at another time.
Next Generation Sequencing (Next-Gen Sequencing)
Current Next Generation Sequencing (NGS) workflows have numerous manual processes that bottleneck throughput and contribute to process inefficiency. One of the most time consuming tasks is gel-based size-selection during the library generation process. In addition to being labor intensive and not scalable, manual methods introduce run-to-run and operator-to-operator variability. Furthermore, the imprecision of this manual excision results in the size selection precision (width of the selected band) being typically no better than ± 10% of the median fragment size (e.g. 400 bp ± 40 bp).
Lab Automation & Liquid Handling
Caliper also offers an extensive portfolio of lab automation and liquid-handling solutions. Our automation systems combine the reliability of robust, industry-standard automation building blocks with modular table foundations to create customized and application-specific workstations with unprecedented flexibility, compactness, throughput and scalability. Caliper's liquid-handling workstations incorporate leading-edge liquid handling technology with unique options and accessories for optimizing a wide array of life science protocols. Our solutions can address fluid volumes as small as 10 nanoliters with outstanding accuracy, ensuring consistent liquid delivery in changing environmental conditions, including temperature and sample viscosity variations.
ZEPHYR GENOMICS WORKSTATION
A robust and simple solution for DNA and RNA applications.
Ideal for:
• DNA extraction • Sequencing purification
• RNA extraction • PCR setup
• Plasmid isolation • Sequencing reaction setup
• PCR purification • Normalization
• PCR sequencing • More…
The Zephyr Genomics Workstation is a powerful solution for automating numerous critical yet routine molecular biology processes such as nucleic acid purification, reaction setup, and normalization. This benchtop workstation is designed to remove many of the technical hurdles of automating these protocols, without sacrificing functionality and flexibility.
Advances in genomics have generated a clear need for higher sample volumes without sacrificing data quality. Automating many of the error prone and routine manual protocols is the logical path, but unfortunately automation often comes with its own challenges, such as learning to program methods for machine execution and planning assays for unattended operation.
The Zephyr Genomics Workstation is the perfect compliment for today's molecular biology laboratories. Whether isolating total RNA, purifying PCR fragments, setting up reactions, or normalizing DNA samples, the Zephyr Genomics Workstation provides a straight forward and simplified approach, which reduces errors and ensures reproducibility.
About Caliper LifeSciences
Caliper Life Sciences (NASDAQ: CALP) is a leading provider of cutting-edge technologies enabling researchers in the life sciences to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper has compiled numerous best-in-class solutions and is aggressively innovating new technologies to bridge the gaps that exist in bringing in vitro assays to in vivo results and ultimately into cures for human disease. With a keen focus on clinically-relevant experimentation, Caliper's portfolio of offerings includes state-of-the-art microfluidics, lab automation & liquid handling, optical imaging technologies, and discovery & development outsourcing solutions.
Our company represents a community of intelligent, highly-motivated people dedicated to working together as a team to improve the human condition through innovation in life sciences research. We maintain world headquarters in Hopkinton, Massachusetts, and direct sales, service and application-support operations in biopharmaceutically-active countries around the globe. Caliper's customers and partners include leading pharmaceutical companies like Pfizer, GlaxoSmithKline, Sanofi-Aventis, Novartis, and AstraZeneca, among others.
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