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Sequel System

PacBio RS II

Sequel System Product Note



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Pacific Biosciences



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Pacific Biosciences

Experience More Comprehensive Genetic Insight

Delivering valuable insights previously unavailable to the scientific community, PacBio Sequencing Systems provide an unmatched depth of genetic information through exceptionally long sequencing reads (average > 10,000 bp) and the highest consensus accuracy available today.

Introducing the Sequel System: high-throughput, cost-effective access to SMRT Sequencing

The Scalable Platform for Single Molecule, Real-Time (SMRT) Sequencing

Accelerate your research with the most comprehensive view of genomes, transcriptomes, and epigenomes from our higher-throughput system. Reduce project costs and timelines as you create higher-quality whole genome assemblies and explore the full size-spectrum of genetic variation.

Pacific Biosystems Sequel product20150910_7921_PacBio_Sequel.CR2The new Sequel System is based on our proven Single Molecule, Real-Time (SMRT) technology and delivers about 7X more reads with 1 million zero-mode waveguides (ZMWs) per SMRT Cell. The Sequel System is ideal for projects such as rapidly and cost-effectively generating high-quality whole genome de novo assemblies.

This innovative sequencing system features automated reagent and SMRT Cell handling and an integrated software suite. pacbio_sequel_front_closed-178x300_web.jpg

The Sequel System has two primary user access points:

  • Sequel touchscreen interface (for initiating and monitoring runs)
  • Sequel workdeck (for loading samples, SMRT Cells, reagents, and disposables

Additional features of the Sequel System include:

  • Intuitive run setup and monitoring tools
  • Run-time flexibility (from 30 minutes to 6 hours per SMRT Cell)
  • Run-size flexibility (from 1 to 16 SMRT Cells per run)
  • Robotic workflow management

The Original Long-Read Sequencer

The PacBio RS II led to groundbreaking research as the scientific community pursued higher-quality genome analysis and studied the full size-spectrum of genetic variation. With this established technology, there are over 850 scientific publications in a variety of research areas, such as human biomedical research, plant and animal genomics, and microbiology.

pacbio-system.pacbio-rs-ii-machine-300x236_web.pngThe PacBio RS II is ideal for whole genome sequencing of small genomes, targeted sequencing, complex population analysis, RNA sequencing of targeted transcripts, and microbial epigenetics.

The PacBio RS II features high-performance optics, automated liquid handling, proprietary SMRT Cells and reagents, and intuitive instrument control software.

The PacBio RS II contains three primary user access points:

  • RS Touch - instrument software with a touchscreen interface (for initiating and monitoring runs)
    Reagent and sample drawer (for plate and sample loading)
    SMRT Cell and tip drawer (for consumables loading)

Additional features of the PacBio RS II include:

  • Intuitive run setup tools
  • Run-time flexibility (from 30 minutes to 6 hours per SMRT Cell)
  • Run-size flexibility (from 1 to 16 SMRT Cells per run)
  • Robotic workflow management

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