Planning an upcoming grant application?
The Millennium Science – 10x Genomics Grant Value Multiplier Program is designed to help Australian and and New Zealand Early and Mid Career Researchers (EMCRs) incorporate single cell and spatial biology into upcoming grant applications and get more value from their research funding.
Register your eligible grant project before submission and include 10x Genomics consumables in your proposed grant budget. If your grant is successfully awarded, you could receive an additional 50% in eligible 10x Genomics consumable value, helping you expand the scope and impact of your research.

Register your grant project using the form below:

Turn your grant funding into more research
Receive an additional 50% in eligible 10x Genomics consumable value, with no maximum cap.

The Grant Value Multiplier scales with your qualifying 10x Genomics purchase. The more eligible 10x Genomics consumables included in your successful grant, the greater the additional value you can unlock.

For example only:
Planning $20,000 of eligible 10x Genomics consumables in your grant?
$20,000 grant budget + $10,000 Grant Value Multiplier = $30,000 total potential 10x Genomics consumable value
That additional value could help you analyse more samples, explore more biology or extend the scope of your study, without increasing the 10x Genomics budget requested in your grant.

The program is open to Australian and New Zealand researchers and research teams preparing eligible competitive research grant applications.
Early and Mid Career Researchers (EMCRs), as defined by the relevant funding scheme or institution, are particularly encouraged to apply.

You may be eligible if you:
• Are an Australian and New Zealand based researcher or research team
• Are preparing an eligible competitive research grant application
• Plan to include eligible 10x Genomics consumables in your proposed project budget
• Register your project with Millennium Science before submitting your grant application
• Proceed with the eligible 10x Genomics purchase if your grant is successfully awarded
Relevant funding opportunities may include ARC, NHMRC and MRFF schemes, as well as eligible university seed and pilot grants, philanthropic grants and disease specific research funding.

Not sure whether your grant is eligible? Register your interest and our team can help.

1. Register your grant project
Tell us about your research, funding scheme and submission deadline.
2. Plan your 10x Genomics component
Our team can help you scope the technology, experimental requirements and indicative budget.
3. Prepare your grant budget
Work with our team to determine indicative 10x Genomics requirements and obtain a quote for your grant application.
4. Include 10x Genomics in your grant application
Submit your application with eligible 10x Genomics consumables included in your proposed project budget.
5. Let us know when your grant is awarded
Once your successful grant and eligible purchase are confirmed, your project can proceed through the Grant Value Multiplier process.
6. Unlock additional research value
Receive additional eligible 10x Genomics consumables equivalent to 50% of the qualifying purchase value, subject to program terms and conditions.

You don’t need to have every detail of your experiment worked out before you register.

Before submission, Millennium Science and 10x Genomics can connect you with support to help plan the 10x Genomics component of your grant, including:
• Experimental scoping based on your research question
• Single cell and spatial technology selection
• Study design and sample planning
• Indicative consumable requirements and quotation support
• Technical resources and relevant publications
• Access to local service providers and core facilities where required
• 1:1 Grant Planning Sessions with our sales and technical teams

Our goal is to help you build a scientifically appropriate and realistically budgeted 10x Genomics component into your proposal.

Whether you’re planning your first single cell experiment, adding spatial biology to an established research program, or looking to increase the scale of your next study, start the conversation before you submit your application.

Register your grant project using the form below:

Have a project in mind but aren’t sure what to include in your grant? Request a 1:1 Grant Planning Session to discuss your project with the Millennium Science and 10x Genomics team.

Eligibility criteria, eligible products, qualifying grant schemes, purchase requirements and redemption periods apply. Participation and multiplier value are subject to approval under the final program terms and conditions. Atera reagents are excluded from the Grant Value Multiplier Program.

Discover how single cell spatial biology is transforming our understanding of colorectal cancer.

The Xenium platform enables researchers to profile gene expression directly within intact tissue, preserving the spatial relationships between tumour, immune and stromal cells that drive disease progression.

Bulk sequencing averages signals across thousands of cells.

Xenium reveals individual cells within their native tissue architecture, allowing researchers to investigate:

✓ Single cell, subcellular resolution• Tumour heterogeneity

✓ Spatial context preserved

✓ FFPE compatible

✓ Human Colon Gene Expression Panel

✓ Custom add-on panels

✓ RNA and protein profiling on the same tissue section

✔ Multiomic RNA and Protein workflow

Xenium spatial transcriptomic analysis of CRC FFPE tissue. (A) RNA transcript density. (B) Multiplexed protein detection via immunofluorescence. (C) RNA clustering. (D) Post-Xenium H&E.

Formalin-fixed, paraffin-embedded (FFPE) human colorectal cancer (CRC) samples were analyzed using the Xenium Human Colon Gene Expression Panel, supplemented with 53 Immuno-Oncology–specific genes, and stained with all Xenium Protein subpanels. Over 1.7 million cells were profiled for both RNA and protein expression.

10x Genomics public datasets

1. High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancer – Oliveira, Michelli Faria de, et al. Nature Genetics 57 (2025): 1512-1523.

Mapping the colorectal tumour microenvironment at single cell resolution

• Identified distinct macrophage populations in different tumour niches
• Revealed spatial interactions between tumour and immune cells
• Uncovered potential biomarkers for immunotherapy and patient stratification

Powered by Visium HD discovery and Xenium single cell validation.

Integrated workflow combining whole transcriptome discovery, single cell profiling, and Xenium spatial validation. Adapted from Oliveira, Michelli Faria de, et al. Nature Genetics 57 (2025): 1512-1523.

2. Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13+ T and CXCL9+ cells after radiotherapy combined with anti-PD-L1 therapy – Sakai, Shunsuke A., et al. British Journal of Cancer 133 (2025): 795-808.

3. Single-cell integration and multi-modal profiling reveals phenotypes and spatial organisation of neutrophils in colorectal cancer – Marteau, Valentin, et al. Cancer Cell 44 (2026): 146-165.

4. Deciphering spatial heterogeneity of patient-derived organoids of colorectal tumors for drug discovery – Norkin, Maxim, et al. bioRxiv (2026), preprint.

5. Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer – Qi, Jingjing, et al. Nature Communications 13 (2022): 1742.

6. Harnessing the tumour microenvironment depicted by histological images to improve cancer prognosis through a deep learning system – Gao, Ruitian, et al. Cell Reports Medicine 5 (2024): 101536.

New to Xenium? 30% OFF your first Xenium kit*

Existing Xenium users? 15% OFF your next Xenium kit*

Orders must be placed by 30 September.

*Excludes Xenium Prime 1k and 2k custom panels. First kit only.

✉ 10xgenomics@mscience.com.au

Clinical research is increasingly driven by the need to understand biological heterogeneity, identify actionable biomarkers, and link molecular mechanisms to patient outcomes. Traditional bulk and low-resolution approaches often mask clinically relevant signals, slowing discovery and translation. 10x Genomics technologies accelerate clinical research by enabling cell-resolved and spatially resolved insights at scale at earlier in the research pipeline.

A targeted Clinician Researcher Accelerator Program designed to support medically qualified clinician researchers in generating high-impact spatial and single-cell data, with dedicated support and preferential pricing to fast-track translational research.

The Clinician Researcher Accelerator Program is a limited-time initiative supporting medically qualified clinician researchers who are looking to integrate spatial transcriptomics and single-cell profiling into their research. Successful applicants will receive access to dedicated technical guidance, and preferential pricing to help generate robust pilot data for translational and clinically focused studies.

Many clinical samples including tumours, immune tissues, and biopsies, are highly heterogeneous. Bulk profiling averages signals across cell populations, obscuring rare or disease-driving cell states.

Chromium Single Cell technologies enable researchers to:

• Identify rare or pathogenic cell populations
• Characterise immune cell diversity and activation states
• Study patient-to-patient variability at cellular resolution

Clinical impact:
Earlier identification of clinically relevant subpopulations improves hypothesis generation, patient stratification strategies, and biomarker discovery.

Understanding where cells are located within tissue is critical for clinical interpretation, particularly in oncology, immunology, and pathology-driven research.

Visium Spatial Gene Expression allows researchers to:

• Map gene expression within intact tissue sections
• Correlate molecular patterns with histology
• Identify spatially distinct disease niches

Clinical impact:
Spatial context strengthens biological interpretation, supports translational relevance, and enables more compelling mechanistic narratives for grants and publications.

Discovery technologies are most powerful when paired with targeted validation in clinically relevant samples.

Xenium In Situ enables:

• High-plex, single-cell resolution spatial validation
• Direct visualisation of clinically relevant gene signatures
• Confirmation of biomarkers within preserved tissue architecture

Clinical impact:
Xenium supports the transition from discovery to validation which is a critical step for translational studies, diagnostic development, and clinical adoption.

Clinical research is often constrained by:

• Limited sample availability
• Ethical and governance considerations
• The need to justify scale and cost upfront

10x Genomics platforms are well suited to small, high-information pilot studies, allowing researchers to:

• De-risk experimental design
• Generate convincing preliminary data
• Strengthen ARC, NHMRC, and translational grant applications

Clinical impact:
High-quality pilot data reduces uncertainty and accelerates progression to larger, funded studies.

Complex clinical questions rarely have single-dimensional answers.

10x Genomics workflows support:

• Integration of transcriptomics, immune profiling, and spatial biology
• Cross-platform studies linking cell state, location, and function
• More comprehensive biological models of disease

Clinical impact:
Multi-modal data improves robustness, reproducibility, and translational relevance which is increasingly expected by reviewers and collaborators.

Clinical research demands consistency, robustness, and scalability.

10x Genomics technologies are:

• Highly standardised and widely adopted
• Supported by validated workflows and protocols
• Designed for reproducible data generation across sites

Clinical impact:
Standardisation supports multi-centre studies and facilitates collaboration between hospitals, academia, and industry.

Graduate students and early to mid-career researchers with no prior hands-on experience using 10x Genomics technologies are invited to apply for the prestigious 2026 Millennium Science – 10x Genomics Fellowship Program.
This Fellowship is designed to support researchers who are keen to adopt cutting-edge single-cell and spatial technologies in their work.

Applications close: 16 March 2026
Outcomes announced: 30 March 2026

The 2026 Fellowship Program focuses on the application of 10x Genomics technologies to FFPE samples, using one or more of the following platforms:
Chromium Single Cell
Visium Spatial 
Xenium In Situ  (NEW within the Fellowship Program!)

If you have any questions, please contact us at fellowship@mscience.com.au.