Also known as PERK; ER-stress sensor kinase that phosphorylates eIF2alpha to attenuate translation during the unfolded protein response. Recombinant human EIF2AK3 (563-1115) was expressed in E. coli cells using an N-terminal GST tag.Store product at –70°C. For optimal storage, aliquot target into smaller quantities. Avoid repeated handling and multiple freeze/thaw cycles.