Phosphatase (Wip1) that dephosphorylates p53 and DNA-damage response proteins, dampening checkpoint signalling; oncogenic when amplified. Recombinant full length human WIP1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Molecular weight 110 kDa. Supplied as sterile 20 mM MOPS, pH 7.5, 300mM NaCl, 10mM glutathione, 0.25-1mM DTT, 0-0.1mM PMSF, 10-25% glycerol. Store product at –70°C. For optimal storage, aliquot target into smaller quantities. Avoid repeated handling and multiple freeze/thaw cycles.