10x Genomics

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  • Technology
  • 10x-MS Fellowships
  • Instruments
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Technology

Chromium

Visium - Spatial Biology

This proprietary Next GEM technology fuels our Chromium System with an innovative reagent delivery system, set of algorithms and turnkey software analysis tools that enable the discovery of previously inaccessible genetic information at massive rate and scale.

The Next GEM technology is built on a new chip architecture that integrates seamlessly into existing solutions. This technology will enable future solutions and product improvements. The Next GEM technology combines new chips and reagents, and is currently offered for the following solutions:

  • Chromium Single Cell Gene Expression
  • Chromium Single Cell Immune Profiling
  • Chromium Single Cell ATAC

Uncover the "where" for every "What".

The relationship between cells and their relative locations within tissue is critical to understanding normal development and disease pathology. Spatial transcriptomics is a groundbreaking molecular profiling method that allows scientists to measure all the gene activity in a tissue sample and map where the activity is occurring. Already this technology is leading to new discoveries that are proving instrumental in helping scientists gain a better understanding of biological processes and disease.

Available for:

  • FFPE samples
  • Fresh Frozen samples

 

Instruments

Chromium X Series

The Chromium X Series lets you access single cell analysis at any stage. From Chromium iX, offering cost-effective, lower throughput single cell analysis, upgradable to the high-throughput full-range Chromium X, we make single cell analysis a perfect fit.

 

Chromium X

The most flexible way to single cell.

https://www.10xgenomics.com/chromium-x/ 

 

Chromium iX

Lower throughput option. 

Not ready for high-throughput studies? Just starting your single cell journey? Not a problem. The Chromium iX member of the Chromium X Series can get you on your way. Conduct pilot studies, early stage research, and everyday single cell experiments. When you’re ready to scale up, you don’t even need to purchase a new instrument—a simple software upgrade is all it takes to move up to Chromium X. The full suite of single cell assays is at your service with the Chromium X Series. There’s no limit to the type and scale of study you can do.

 

Chromium Controller

 

 

Chromium Connect

 

Products

Chromium Single Cell Gene Expression

 

Chromium Single Cell Gene Expression provides single cell transcriptome 3' gene expression and multiomic capabilities to profile tens of thousands of cells. Explore cellular heterogeneity, novel targets, and biomarkers with combined gene expression, surface protein expression, or CRISPR edits in each cell.

 

 

 

Explore what you can do: Technology Features:
  • Characterise complex cell populations
  • Discover novel cell types and states
  • Unravel complex cellular processes
  • Scalable functional genomics
  • Single Cell Resolution at Scale 
  • Multiomic Cellular Readout
  • Scalable Functional Genomics 
  • Streamlined Data Analysis
  • One-day Lab Workflow 
  • Diverse Sample Compatibility 

Download Product Sheet

https://www.10xgenomics.com/products/single-cell-gene-expression 

 

Single Cell Gene Expression LT

Getting started with Single Cell Gene Expression?

Run pilot studies or optimize future experiments with an affordable solution for small-scale projects.

https://pages.10xgenomics.com/rs/446-PBO-704/images/10x_LIT000120_Product_Sheet_LT_Kit_Letter_Digital.pdf 

 

Multiomic analysis

Simultaneously measure cell surface protein expression or CRISPR perturbations with 3’ gene expression.

CRISPR Screening

Assess effects of CRISPR perturbations at single cell resolution with direct capture of cellular sgRNAs and changes in gene expression.

https://cdn.10xgenomics.com/image/upload/v1594137695/products/10x_LIT093_Product-Sheet_Explore-Cellular-Diversity_Letter_digital.pdf 

Cell Surface Protein

Explore combined single cell gene and protein expression to enable discovery of novel cell subsets and rare cell populations. 

https://cdn.10xgenomics.com/image/upload/v1594137695/products/10x_LIT093_Product-Sheet_Explore-Cellular-Diversity_Letter_digital.pdf

 

Large-scale projects

Tackle your most ambitious projects, from drug screening to pre-clinical trials, with complementary solutions for larger-scale projects.

Single Cell Gene Expression HT

Expand your experimental possibilities and make million-cell studies routine with high-throughput (HT) gene expression and multiomic analysis on the new Chromium X.

https://pages.10xgenomics.com/rs/446-PBO-704/images/10x_LIT000126_Product_Sheet_Single_Cell_GE_HT_Kit.pdf

Targeted Gene Expression

Profile a defined set of transcripts to reduce costs while increasing sample number or sequencing depth with customisable, comprehensive gene panels.

 

Sample Multiplexing with 3' CellPlex

 

 

 

 

 

 

 

 

 

 

FAQs

What is the minimum and maximum number of cells that can be profiled for single cell assays?

What is the best way to count cells?

Can Cells be Sorted Prior to Running Through the 10x Single Cell Assay?

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