Millennium Science
Enabling next-generation research
- NanoAb Service
- Antibodies
- Reagent Product Custom Services
- DNA
- RNA
- Proteins/Peptides
- Beads/Dyes
- Lysates/Slides
- Antibody Pairs/Kits
- Antibody Arrays
- IHC/Pathology Ab
- Circulating Rare Cell Ab
- In Situ Hybridisation
- Systems & Automations
- GMP/ASR/IVD
NanoAb Service
VHH antibody, also known as Camelid single domain antibody (sdAb), is the recombinant variable domain derived from camelid heavy-chain-only antibody. This configuration confers a number of unique properties. The small size and high stability of VHH antibody make it a promising tool for disease diagnosis and treatment. VHH antibody can penetrate tissue more easily and target difficult epitopes hidden in the protein structure. Additionally, VHH antibody expresses well in many host systems, making it cost-effective for large-scale manufacturing.
Abnova offers the NanoAb™ service for the production of target-specific VHH antibodies from the camelid VHH library. Using advanced camelid VHH library screening technology, we screen the library and isolate the VHH clones for your required antigens. Positive clones are sequenced and validated by ELISA. The selected clones will then be introduced into the HEK293 expression vector or E. coli expression vector for transient and scalable VHH antibody production, suitable for many downstream applications.
NanoAb workflow
Specifications
Advantages
- Small Size
- Low Immunogenicity
- Fast Blood Clearance
- Easy Conjugation
- Robustness in Bioengineering
- Superior Stability
- High Affinity and Specificity
- Versatile Production
- Easy Multimerization (Multivalency/Multiparatopicity/Multispecificity)
- Applications Across Fields
VHH Antibody vs. Conventional Mab and Pab
Antibodies
Polyclonal Ab - Bovine, Human, Microbe, Mouse, Phospho-Specific, Rabbit, Rat, Small Molecule, Virus, Zebrafish, Others, Idiotype, CRISPR
Monoclonal Ab - Bovine, Chicken, Human, Idiotype, Isotype Control, Microbe, Mouse, Phospho-Specific, Rabbit, Rat, Sheep, Small Molecule, Virus, Others, Made to order, CRISPR
MaxPab Ab - Human, Isotype Controls, Made to order
DNAxPab - Human, Made to order
Recombinant Ab - Human, Isotype Control, Microbe, Mouse, Small Molecule, Tag, Virus, Others
Conjugate Ab - Human, Isotype Control, Mouse, Rat, Others, Idiotype, CRISPR
Secondary/Tag Ab - Conjugate Secondary Ab, Secondary Ab, Tag Ab, Conjugated Tag Ab
Reagent Product Custom Services
DNA
- DNA Extraction Kits
- Electrophoresis reagents
- Markers
- PCR
- Transfection
RNA
- Total RNA
- Electrophoresis
- Markers
- miRNA
- IncRNA
- In vitro transcription (IVT)
Proteins/Peptides
Abnova have >28,780 proteins/peptides for your research needs. Applications may include: ELISA, WB, AP, Array, SDS-PAGE, Enzyme, etc.
- Bacteria
- Enzymes
- Human
- Mouse
- Rat
- Virus
- Yeast
- Others
- Tools
- Made to order
Beads/Dyes
Fluorescent Dyes - for Cell staining, Conjugation, Flow Cytometry, IVI, etc
Magnetic Beads - for Purification, Conjugation, IP, Separation
- 8-channel cover strip
- 96 deep well plate (Polypropylene)
- CSV magnetic beads
- MaxBead Carboxyl Labelling Kit
- MaxBead Protein A
- Oligo (dT)30 Magnetic Microspheres
- PSMA magnetic beads
Lysates/Slides
- Lysates - Cell Line, Mammalian Over Expression, Stem Cell, Tissue
- FFPE Tissue Slides - Human
- Frozen Tissue Slides - Human
Antibody Pairs/Kits
- Ab Array Det Kits
- Ab Drug ELISA Kits
- Ab Labeling Kits
- Ab Pairs for ELISA
- Ab Pairs for IP-WB
- Ab Pairs for PP
- Ab Pairs for PPI
- Assay Kits
- Cell-Based ELISA Kits
- CLIA Kits
- Complement ELISA Kits
- CRISPR Kits
- DNA-Binding ELISA Kits
- ELISA Kits
- ELISpot Kits
- IHC Kits
- IP & ChIP Kits
- Protein Expression Kits
- Phospho-Specific Kits
- Rapid Tests
- TDAR ELISA Kits
Antibody Arrays
IHC/Pathology Ab
IHC Antibodies - Angiogenesis, Apoptosis, Binding, Cell Ad/Junc/Cytoskel, Cell Cycle, Cytokine, Enzyme, Membrane, Metabolism, Neurobiology, Plasma/Serum, Stem Cell, Signal Transduction, Transcriptions, Ubiquitin, Others
Pathology Antibodies - Apoptosis, Cell Ad/Junc/Cytoskel, Cell Cycle, Cell Specific, Companion Diagnostics, Cytokine, Drug Resistance, Hormone Receptor, Tissue Specific, Tumour Marker, Others
Circulating Rare Cell Ab
- Cancer Stem Cell
- Circulating Endothelial Cell
- Circulating Featal Cell
- Circulating Hematopoietic Stem and Progenitor Cell
- Circulating Mesenchymal Stem Cell
- Circulating Tumour Cell
- Circulating Cell Tissue of Origin
In Situ Hybridisation
- Accessory Kits & Reagents
- Chromosome (CEN) CISH Probes
- Chromosome (CEN) FISH Probes
- Control CISH Probes
- Gene CISH Probes
- Gene FISH Probes
- mutaFISH™ Probes
- Prenatal FISH Probes
- Split CISH Probes
- Split FISH Probes
- Subtelomere FISH Probes
- Translocation FISH Probes
- Made to Order FISH Probes
Systems & Automations
- Spiraltor™ 48 - Spiral-Mix Magnetic Bead Handling
- Precipitor™ 32 Plus - High Throughput Extraction, Purification, and Precipitation
- ProteoScreen® - Antibody for Tissue Microarray
- CytoPrep™ - Microfluidic Chip Sample Preparation Automation
- CytoQuest™ CR - Circulating Rare Cell Positive Enrichment & Retrieval System
- CytoView™ - All-in-One Imaging System with Artificial Intelligence Solution
- LiquidCell™ - Negative Enrichment Cell Isolation and Retrieval System
- Protemist® DT II - High Throughput Protein Expression
- RapidScan™ One Reader
- SpiralPipet™ - Spiral-Mix Magnetic Bead Handling System
