CRISPR Guide RNA
Guide RNAs program Cas9 nucleases to cut at a specific genomic location. The design of an effective, functional guide RNA is critical to achieving specific gene knockout.
Synthetic crRNA
Pre-designed or custom synthesized for rapid knockout studies across many genes.
Lentiviral sgRNA
Pre-designed or custom sgRNA as glycerol stocks and high-titer purified lentiviral particles for small- and large-scale studies.
Synthetic sgRNA
Custom single guide RNA oligos for CRISPR-Cas9 gene editing.
Cas9 Nuclease
Active expression of the Cas9 endonuclease is a critical requirement for efficient gene editing. The Edir-R portfolio of Cas9 nuclease expression vectors includes six SMARTchoice constitutive promoter options or an inducible format, providing the felibility to select an optimal system for robust expression and maximal cleavage efficiency when Edit-R guide RNAs are introduced into the cell.
Edit-R Cas9 Nuclease Expression reagents
Non-lentiviral vectors provided as endotoxin-free purified DNA for direct co-transfection with Edit-R synthetic crRNA and tracrRNA.
Edit-R Lentiviral Cas9 Nuclease reagents
Purified lentiviral particles or plasmid DNA for generation of stable Cas9 nuclease-expressing cell populations. Constitutive or inducible promoter options are available.
Edit-RCas9 Nuclease mRNA
Purified Cas9 mRNA for transient Cas9 Nuclease expression
Edit-R Cas9 Nuclease protein NLS
Purified Cas9 protein ready to use for DNA-free nuclease expression.
CRISPR Controls and Detection Primers
Proper controls are essential for every type of experiment to ensure optimal conditions and proper assessment of results.
Edit-R Synthetic Positive crRNA Controls and Detection Primers
Species-specific crRNAs targeting well-characterized genes, as well as mismatch detection assay primers, to determine the effectiveness of your gene editing conditions for maximal efficiency.
Edit-R Synthetic crRNA Non-targeting Controls
Non-targeting controls to evaluate cellular responses to CRISPR-Cas9 Components in the absence of gene target-specific crRNA.
Edit-R Lentiviral sgRNA Positive Controls
Species-specific sgRNAs targeting well-characterised genes to determine the effectiveness of your gene editing conditions for maximal efficiency.
Edit-R Lentiviral sgRNA Non-targeting Controls
Non-targeting controls to evaluate cellular responses to CRISPR-Cas9 components in the absence of gene target-specific sgRNA.
CRISPR-Cas9 Screening Libraries
Investigation of entire gene families of biological pathways is enabled by the broad suite of custom and pre-defined libraries of CRISPR-Cas9 reagents. Both pooled and arrayed screens can take advantage of our algorithm-optimised guide RNA designs for high functionality and superior specificity.
Edit-R crRNA Libraries
Plated pre-defined collections of popular human and mouse gene families for arrayed knockout screening.
Cherry-pick crRNA libraries
Customize and order plates of predesigned crRNA for knockout studies for your targets of interest.
Edit-R tracrRNA
The Edit-R trans-activating CRISPR RNA (tracrRNA) is a chemically synthesised and HPLC-purified long RNA required for use with synthetic crRNA to form the complex that programs Cas9 nuclease.
Edit-R Synthetic sgRNA
Custom synthetic 100-mer single guide RNA, input your own design or use our flexible design tools
Edit-R Pooled Lentiviral sgRNA Libraries
High-titer pooled screening libraries for pre-defined gene sets in human and mouse
HDR Donor Templates
Synthetic single-stranded DNA oligonucleotide (ssDNA oligo) donors for precise genomic modification with the homology-directed repair (HDR) pathway.
EDit-R HDR Donor Designer
Design and order the donor oligo required for precision insertion, removal or replacement of genomic DNA.
CRISPR RNA Configurator
Place a custom gRNA order, or design and order your own crRNA or lentiviral sgRNA with the easy-to-use interface.