Linked-Reads Genomics

Product List




Genome


genome-solution-suite.pngDiscover what you have been missing

The Chromium Genome uses the power of Linked-Reads to fully resolve genic phasing, reveal structural variation and detect variants in previously inaccessible and complex regions of the genome.


Features:

  • Long-range information from a short-read Illumina® sequencer
  • High-quality libraries from as little as 1ng of genomic DNA
  • Turn-key analysis pipeline and visualisation tools
  • Call and phase major classes of structural variants (SVs) like deletions, inversions, and translocations, even in genes inaccessible to short-read sequencers.
  • Phase SNVs, indels and SVs across >10Mb haplotype blocks



Workflow:

genome-workflow.jpg




Exome


genome-solution-suite.pngBeyond the standard Exome

The Chromium Exome provides long range information, enabling phasing, structural variant detection and copy number determination. Low complexity and repetitive regions previously missed with short-read sequencing are now accessible.


Features:

  • High-quality libraries from only 1ng of genomic DNA
  • Detect large scale structural variants (SVs) including gene fusions
  • Call and phase variants across the entire exome
  • Detect variants in genes inaccessible to standard short-read libraries
  • Useful for high sequence homology, including problematic duplications, inversions and pseudogenes
  • Optimsed baits utilise Linked-Reads for intron-spanning



Workflow:

exome-workflow.jpg




De Novo


genome-solution-suite.pngTrue diploid assembly with the supernova assembler

Discover the true genome with the Supernova Assembler and open the door to low-cost, everyday diploid assemblies. Unlock sample-specific sequences, probe diploid genome structure and remove the need for a reference sequence of any kind.


Features:

  • True diploid assembly unlike other methods
  • Fast and simple de novo assembly workflow
  • Go from sample to assembly in <2 weeks
  • 10Mb scaffold size and long range accuracy
  • High-quality assembly from as little as 1ng of DNA
  • Validated and supported for human genomes



Workflow:

assembly-workflow.jpg



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