Single Cell Epigenomics

Chromatin Accessibility


Reveal chromatin accessibility cell by cell with single cell epigenomics

single-cell-atac-solution-with-monitor.pngThe Chromium Single Cell ATAC (Assay for Transposase Accessible Chromatin) Solution accelerates the understanding of the regulatory landscape of the genome, thereby providing insights into cell variability. The chromatin profiling of tens of thousands of single cells in parallel allows researchers to see how chromatin compaction and DNA-binding proteins regulate gene expression at high resolution.

The Chromium Single Cell ATAC Solution also includes intuitive software analysis and visualization tools for a refined analysis of gene regulatory networks in single cells. The Chromium Single Cell ATAC Solution can be used to study developmental plasticity, cellular heterogeneity, and beyond.


  • Discover cellular heterogeneity stemming from epigenetic variability
  • Better understand the gene regulatory networks that are upstream of gene expression
  • Define cell types and states for lineage and developmental program tracing
  • Accelerate biomarker discovery



Benefits:

  • Detect open chromatin regions in single cells with enriched signals in Transcription Start Sites (TSS) and regulatory regions.
  • Profile 500 to 10,000 nuclei per channel with the scalable, high-throughput solution.
  • Recover up to 65% of nuclei loaded on chips.
  • Investigate cell lines, primary cells, fresh, and cryopreserved samples with confidence
  • Analyse your single cell epigenetic data with the turnkey analysis software and interactive visulisation tools.



Workflow:

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