SoftGenetics

Software PowerTools for Genetic Analysis

We offer leading edge software powertools for genetic analysis, such as Mutation Surveyor® DNA variant analysis of Sanger Sequencing software, NextGENe® 2nd Generation Sequence Analysis software, Geneticist Assistant NGS Interpretative Workbench, GeneMarker® the "Biologist Friendly" Genotyping software, GeneMarker®HID STR Human Identity software, ChimerMarker® Automated Chimerism Analysis software, and JelMarker™ Image Reading and Conversion software.

Get Your FREE 35-day Software Trial Here


Product List


ChimeRMarker - Automated Chimerism Analysis Software

chimermarker_logo.jpgChimeRMarker integrates speed and accuracy with a biologist-friendly interface. The software can be used to monitor chimerism level in both allogeneic and autologous stem cells transplant (SCT) or hematopoietic stem cells transplant (HSCT), bone marrow transplant (BMT), and cord and peripheral blood stem cells transplant (PBSCT) samples. The program provides accurate, rapid genotyping and chimerism analysis; automatically identifies donor and recipient peaks in post-BMT samples, calculates percent chimerism and quality metrics for single donor or double donor cases, easily appends for longitudinal monitoring post-BMT, and has multi-lineage capabilities for chimerism analysis of T-cells, B-cells, and other cell type populations. ChimerMarker software includes functions for comparison of samples at different time points to conduct longitudinal studies for monitoring each individual and a comprehensive chimerism analysis report. Chimerism analysis is completely linked to the main analysis screen, removing the error-prone step of data transfer from genotyping software to chimerism analysis software.

FREE 35-day Software Trial

Downloads

Videos

GeneMarker® - The Biologist Friendly Software

pic_gm.jpgGeneMarker® software is a unique genotype analysis software which integrates new technologies enhancing the speed, accuracy and ease of analysis. Biologist-friendly, the software is compatible with outputs from all major sequencing systems. Incorporated tools include Kinship Analysis of Wild Populations; Phylogeny Clustering; Project Comparison; as well as a User Management providing an analysis audit trail and editing.

FREE 35-day Software Trial

Downloads

Videos



GeneMarker HID - Human Identity Software

genemarkerhid.jpgGeneMarker HID is an excellent choice for all forensic profiling applications. This expert system software can be employed as a "biologist-friendly" replacement for GeneScan®/GenoTyper® or as an alternative to GeneMapper® ID and GeneMapper® IDX human identification software, reducing analyst required edits by 18-73% per sample. In addition to standard STR analysis, GeneMarker HID software has been optimized to analyze profiles from YSTRs, Low Copy Number LCN samples, ABI's MiniFiler™ Kit, and replicate sample consensus. GeneMarker HID software includes applications to assist experts with Mixture Analysis. Relationship testing and database searching for matching/near matching profiles and familial search capabilities, which are essential for crime scene investigation, missing persons identification and paternity testing. GeneMarker HID software has been validated by forensic labs world-wide and has many time-saving tools, including an automated contamination check, to reduce casework backlogs and analyst fatigue.

FREE 35-day Software Trial

Downloads

Links

Videos



GeneMarker HTS - Mitochondrial NGS Analysis Software

gmhts.pngGeneMarker®HTS (High Throughput Sequencing) software provides a streamlined workflow for forensic and medical research mitochondrial DNA data analysis from massively parallel sequencing (MPS) systems in an easy to use Windows® operating system. Developed in collaboration with leading laboratories, GeneMarkerHTS software provides rapid analysis of multiple samples using consensus alignment or a unique motif alignment technology that automates the recommendations of DNA Commission of the International Society for Forensic Genetics: Revised and extended guidelines for mitochondrial DNA typing. Using forensic motif alignment fulfills the maximum parsimony approach of forensic alignment, and provides recognition and proper assignment of motifs and INDELs consistent with phylogenetic and forensic considerations.

FREE 35-day Software Trial

Downloads

Links

Videos



GeneMarker MTP - Multi-Template Processor

pic_mtp.jpgGeneMarker MTP provides the analysis power of six GeneMarker programs; reducing costs while increasing efficiency of DNA fragment analysis. The automated import and assignment of analysis parameters (templates) is intuitive, reducing complexity and analysis time. GeneMarker MTP maximizes the utility of a CE plate - include up to 6 different chemistries on the same plate. GeneMarker MTP is rapid - processing six 96 well CE plates in approximately 30 seconds. GeneMarker MTP is compatible with custom and commercial chemistries, and all major capillary electrophoresis platforms.

FREE 35-day Software Trial

Downloads

Videos



Geneticist Assistant™ - NGS Interpretative Workbench

pic_ga.jpgGeneticist Assistant NGS Interpretative Workbench is a unique tool for the management, control, visualization, functional interpretation and historical knowledge base of next generation sequencing Whole Exome data or targeted at specific genes for the purpose of identifying potentially pathogenic variants associated with specific conditions such as hereditary colon cancer and others. Geneticist Assistant is compatible with data processed from all leading next generation sequencing platforms and the program accepts standardized BAM and VCF files. The new administration function provides a real-time tracking of current statuses; historical information; automated email notifications within a completely customisable work flow built to model your actual activities. Unique tools include CAP Validation Assistance, automated .BED file builder which automatically highlights areas of clinical significance, Positive Control Verification, and in conjunction with NextGENe software can form a completely automated informatics pipeline.

FREE 35-day Software Trial

Videos



JelMarker - Image Reading & Conversion Software

pic_jm.jpgIt was developed in response to a growing demand for software that can analys0-e fluorescence, chemiluminescence and autoradiography gel image files. With JelMarker you can import up to two TIFF, BIP, JPEG, and TXT files for simultaneous analysis. JelMarker™ exports SCF files for easy upload to the fragment analysis software GeneMarker®. JelMarker™ is a simple, stand-alone image reading software providing highly accurate lane and band recognition. It has easy to modify lane and band positions with the use of point-and-click methodology.

FREE 35-day Software Trial

Downloads

Videos



MaSTR™

mastr.jpgMaSTR™ Enlightened Probabilistic Mixture Analysis Software. MaSTR software features a rapid and transparent approach to Probabilistic Mixture Analysis which utilizes your forensic acumen in an easy-to-use Windows® environment for research, validation and casework applications. Server based MaSTR software is very cost effective, includes two simultaneous user licenses, and automatic queuing of multiple analyses.

Downloads

Links



Mutation Surveyor® - DNA Variant Analysis Software

index.jpgMutation Surveyor® software is a powerful and accurate DNA Sequencing analysis tool for Sanger Sequencing files. Capable of performing variant analysis of up to 2000 Sanger sequencing files in 15 minutes, Mutation Surveyor delivers excellent accuracy, sensitivity, and low false positive and false negative rates in the analysis of DNA variants, including: single nucleotide polymorphisms (SNPs), insertions and deletions (INDELS), and somatic mutations in direct sequencing, PCR sequencing, Mitochondrial DNA sequencing, and resequencing projects. The package includes patented anti-correlation technology, which physically compares sample sequence traces to a reference trace, providing accuracy up to 99.5% with Phred 20 bi-directional sequences and a sensitivity of 5% of the primary peak.

Mutation Surveyor software version 5.0 includes new features designed to enhance and optimize the process of variant discovery in Sanger sequencing traces. Included in version 5.0 is a new variant knowledge database, which allows users to track variants by chromosomal position, indicate false-positives and other artifacts, and query mutation database information from popular variant databases. Also included in Mutation Surveyor software version 5.0 is a user management system, which enables administrators to set up password protected user names, control access rights, and generate a user audit trail for each analysis project. Access rights for each user are determined by the administrator, providing assurance that unauthorized individuals do not accidentally alter a project or change the analysis parameters established by the laboratory. User management also provides user ID and Organization in the header of the final reports. Each change to the project is captured by user and time stamped.

FREE 35-day Software Trial




NextGENe® - 2nd Generation Sequence Analysis Software

nextgene-logo.jpgNextGENe is the perfect analytical partner for the analysis of desktop sequencing data produced by many different platforms. NextGENe software runs on a Windows® Operating System, which provides a biologist-friendly point & click interface, and does not require scripting or other bioinformatics support. The software employs unique platform specific technologies in one free-standing multi -application package.

FREE 35-day Software Trial

Downloads

Links