Unchained Labs

On this page:

Solutions

  • Biologics
  • Gene Therapy
  • Cell Therapy
  • LNPs
  • Genomics
  • Automation

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Leprechaun - Lentivirus titre and structure 

The unmatched lentivirus and exosome characterisation tool.

Lentivirus

  • Titer
  • Structure
  • RNA content
  • Contaminant analysis

Exosomes

  • Size
  • Concentration
  • Phenotype

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Lunatic - Quantification

The next-gen protein and nucleic acid quantification system.

  • 2 µL volume
  • 96 samples
  • 10 minutes
  • SBS plate format

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Stunner - Quantification and sizing

The ultimate quantification and sizing tool.

LNPs

  • Sizing & polydispersity
  • Particle concentration
  • Aggregation
  • Total RNA quant

Biologics

  • Protein quant
  • Sizing & polydispersity
  • Molecular weight
  • Aggregation detection
  • B22 & kD
  • Conjugate characterisation

Viral Vectors

  • Capsid titre
  • Empty/full ratio
  • Aggregation
  • Sizing & polydispersity

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Uncle - Stability

The first all-in-one biologics stability screening platform.

  • Tm & T agg
  • Isothermal stability
  • Viral capsid stability
  • Tm with SYPRO (DSF)
  • Sizing & polydispersity
  • Sizing with thermal ramp
  • Thermal recovery
  • Viscosity
  • kD
  • B22
  • G22
  • ΔG

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Unagi - Buffer exchange

The only completely hands-free benchtop buffer exchange solution.

  • Protein
  • mRNA & DNA
  • AAV
  • LNP

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Big Tuna - Plate-based buffer exchange

The ultimate automated buffer exchange solution.

  • AAV
  • LNP
  • VLP
  • mRNA & DNA
  • Protein

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Honeybun - Viscosity

The most rapid viscometer out there.

  • 10 at a time
  • 35 μL per sample
  • 1 minute runs (≤10 cP)
  • Up to 150 cP

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Junior - Configurable benchtop automation

The all-around configurable benchtop workflow solution.

  • Formulation screening and optimisation
  • Visual inspection
  • Sample preparation
  • Reaction screening
  • Powder dispensing
  • Pressurised reactors
  • Process chemistry

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Big Kahuna - Configurable end-to-end workflow solution

The most customisable automated workflow solution.

  • Formulation screening and optimisation
  • Visual inspection
  • Sample preparation
  • Reaction screening
  • Powder dispensing
  • Pressurised reactors
  • Process chemistry

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Sunscreen - Automated formulation screening

The primo LNP formulation screener.

  • 96 formulations in <6 hours
  • 200 μL – 2 mL per experiment
  • 0.1 – 30 mL/min flow rates
  • Reusable microfluidics
  • Scalable method

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Sunshine - Formulation optimisation and scale-up

The all-around LNP process developer.

  • 10 experiments in 15 minutes
  • Fractional & total flow rates
  • 1 mL to continuous flow
  • 0.1 — 30 mL/min flow rates
  • Reusable microfluidics
  • Protocol transfer from Sunscreen

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