Seeing More, Doing More: Agilent’s BioTek Imaging Portfolio in Action!

A Joe Blogs post by Joe Roberts, PhD

Modern life science research increasingly demands more information from fewer samples, delivered faster and with greater confidence. Whether you’re studying immune cell function, complex 3D models, or subtle phenotypic changes, imaging is central to generating meaningful insights. Agilent’s BioTek imaging portfolio is designed to meet this challenge, combining high-quality microscopy, flexible multimode detection, and live-cell capability into integrated platforms that scale with your research needs.

Cytation and Lionheart: Imaging Platforms That Scale With Your Research

The Agilent BioTek Cytation™ range spans entry-level widefield imaging through to advanced confocal workflows, combining automated microscopy with multimode microplate reading in a single, integrated platform. Designed to scale with experimental complexity, Cytation systems support routine plate-based assays, high-content imaging, and live-cell experiments with environmental control, making them suitable for laboratories of all sizes and budgets.

For labs requiring dedicated automated microscopy, the Agilent BioTek Lionheart™ FX and LX microscopes deliver high-performance imaging in a compact footprint. These systems support a wide range of objectives and imaging modalities, with robust autofocus, flexible incubation options, and automation-ready workflows. Lionheart platforms are particularly well suited to phenotypic profiling, kinetic assays, and live-cell imaging where precision and repeatability are essential.

A detailed product comparison table below highlights the specific capabilities of each Cytation and Lionheart model.

A detailed product comparison table below highlights the specific capabilities of each Cytation and Lionheart model.

Why Agilent BioTek Imaging Stands Out

Across the portfolio, Agilent imaging platforms share several key advantages:

  • Support for 6- to 1536-well plates, slides, dishes, and flasks.
  • Compatibility with automation solutions like BioStack™, BioSpa™, and BenchCel™.
  • Live-cell imaging with CO₂/O₂ control, shaking, and temperature incubation.
  • Advanced imaging capabilities: Z-stacking, Z-projection, montage stitching, and time-lapse videos.
  • Hybrid optics for sensitive and specific fluorescence detection.

Applications include wound healing assays, cell migration and invasion studies, immunofluorescence, neurite outgrowth analysis, 3D cell models, and ADME/Tox experiments. By unifying imaging and detection in a single platform, Agilent BioTek systems help labs move beyond single-endpoint measurements to richer, biologically meaningful data.

Joe’s Takeaway

Whether you’re starting with simple plate-based assays or pushing the boundaries of confocal or automated microscopy, the Agilent BioTek imaging portfolio gives you the flexibility, performance, and scalability to see more and do more.

If you’re interested in a demo, contact us today!

Until next time… happy experimenting!

Joe Blogs