Mabtech IRIS 2 in Immunology Research: Insights from Dr Liam Kealy

Introduction

When accuracy, sensitivity, and throughput matter, immunologists are turning to advanced platforms like the Mabtech IRIS 2. Dr. Liam Kealy, Postdoctoral Researcher at Monash University, recently shared his insights into how the IRIS 2 elevated his work on plasma cells and antibody secretion and his experience working with Millennium Science. His testimonial highlights why the IRIS 2 is considered a gold standard for ELISpot, FluoroSpot, and viral focus-formation assays.

Dr Liam Kealy using the Mabtech Iris 2Dr Liam Kealy

The Research Challenge: Studying Plasma Cells and Antibodies

Before adopting the Mabtech IRIS 2, Dr. Kealy and his team faced a significant challenge: the need for a multiplex approach to directly study plasma cells and the diverse antibodies they secrete. Conventional workflows lacked the flexibility and precision required for such complex immunology studies.

Gold-Standard Accuracy in Spot Detection

The Mabtech IRIS 2 solved this challenge by providing high-throughput, accurate, and user-friendly spot detection. According to Dr. Kealy:

“The IRIS 2 by Mabtech stands as the gold standard in spot detection and analysis. Equipped with advanced software, it enables high-throughput spot counting with unparalleled accuracy. Moreover, it is capable of detecting up to four colours and can provide users with additional metrics like relative spot volume.”

Applications in Immunology

This capability has opened new possibilities for his research, including ELISpots, FluoroSpots, and viral focus-formation assays. With its ability to measure multiple analytes simultaneously, the IRIS 2 enables researchers to collect richer datasets while saving time and samples.

ELISpot-and-FluoroSpot

Advanced Analysis with the Mabtech IRIS 2

The intuitive interface and advanced software tools mean researchers can move seamlessly from data acquisition to analysis. For immunologists studying antibody secretion, vaccine responses, or infectious disease mechanisms, this efficiency translates to deeper insights and faster progress.

Experience working with Millennium Science

Equally important, the collaboration with Millennium Science has played a role in supporting Dr. Kealy’s research goals. He notes:

“I always immensely enjoy chatting science with Millennium Science and working with their team to design bespoke strategies to tackle my research questions.”

Dr-Liam-Kealy-and-Dr-Joe-Roberts

Takeaway

For researchers seeking accuracy, flexibility, and high-throughput performance in multiplex immunology assays, the Mabtech IRIS 2 offers a user-friendly solution trusted by leading scientists.